MSH6 FISH Probe
产品名称: MSH6 FISH Probe
英文名称: MSH6 FISH Probe
产品编号: FA0066
产品价格: 0
产品产地: 台湾
品牌商标: Abnova
更新时间: null
使用范围: null
亚诺法生技股份有限公司(Abnova)
- 联系人 :
- 地址 : 台湾台北市内湖区洲子街 108 号 9 楼
- 邮编 : 11493
- 所在区域 : 台湾
- 电话 : +886-920**1152 点击查看
- 传真 : 点击查看
- 邮箱 : sales@abnova.com.tw
- Specification
- Product Description:
- Made to order FISH probes for identification of gene amplification using Fluorescent In Situ Hybridization Technique. (Technology)
- Storage Instruction:
- Store at 4°C in the dark.
- Supplied Product:
- DAPI Counterstain (1500 ng/mL ) 250 uL
- Origin:
- Human
- Source:
- Genomic DNA
- Regulation Status:
- For research use only (RUO)
- Applications
- Fluorescent In Situ Hybridization (Cell)
- Protocol Download
- Application Image
- Fluorescent In Situ Hybridization (Cell)
- Entrez GeneID:
- 2956
- Gene Name:
- MSH6
- Gene Alias:
- GTBP,HNPCC5,HSAP
- Gene Description:
- mutS homolog 6 (E. coli)
- Omim ID:
- 600678
- Gene Ontology:
- Hyperlink
- Gene Summary:
- This gene encodes a protein similar to the MutS protein. In E. coli, the MutS protein helps in the recognition of mismatched nucleotides, prior to their repair. A highly conserved region of approximately 150 aa, called the Walker-A adenine nucleotide binding motif, exists in MutS homologs. The encoded protein of this gene combines with MSH2 to form a mismatch recognition complex that functions as a bidirectional molecular switch that exchanges ADP and ATP as DNA mismatches are bound and dissociated. Mutations in this gene have been identified in individuals with hereditary nonpolyposis colon cancer (HNPCC) and endometrial cancer. [provided by RefSeq
- Other Designations:
- G/T mismatch-binding protein,mutS homolog 6,sperm-associated protein
- Gene Pathway
- Related Disease
- Adenocarcinoma
- Adenoma
- Adenomatous Polyposis Coli
- Anticipation, Genetic
- Ataxia telangiectasia
- Breast cancer
- Breast Neoplasms
- Carcinoma
- Carcinoma, Papillary
- Chromosomal Instability
- Colon cancer
- Colonic Neoplasms
- Colonic Polyps
- Colorectal Neoplasms
- Colorectal Neoplasms, Hereditary Nonpolyposis
- Cystadenocarcinoma, Serous
- Disease Progression
- Duodenal Neoplasms
- Endometrial Neoplasms